Dr Sophie Otter is a Consultant Clinical Oncologist at Royal Surrey County Hospital, with outreach services at Ashford and St Peter’s Hospitals. She previously served as Chief of Service for Oncology. Her clinical focus includes the treatment of urological cancers—particularly prostate and bladder—as well as colorectal cancers. She is experienced in delivering advanced therapies such as prostate brachytherapy, intensity-modulated radiotherapy (IMRT), and systemic treatments including chemotherapy, immunotherapy, and hormone therapy.

She graduated from the University of Cambridge in 2004 with distinctions in Medicine, Surgery, and Pathology. Her oncology training took place at Guy’s and St Thomas’ Hospitals and the Royal Marsden Hospital. She earned an MSc in Oncology with distinction in 2014 and completed an MD (Res) at the University of Surrey, focusing on image-guided radiotherapy for pelvic tumours.

Dr Otter’s research interests span image-guided radiotherapy, brachytherapy for pelvic malignancies, and the use of biomarkers and immunotherapy in cervical cancer. She has published extensively in peer-reviewed journals and contributed to leading oncology textbooks. Her work has been recognised through multiple fellowships and travel grants, including awards from ESTRO and the Royal College of Radiologists.

She is a Fellow of the Royal College of Radiologists and a Member of both the Royal College of Physicians and ESTRO. Her commitment to clinical excellence and innovation in cancer care has made her a respected figure in the oncology community, particularly in advancing brachytherapy and precision radiotherapy techniques.

Professor Langley was appointed Consultant Urological Surgeon at the Royal Surrey County Hospital, Guildford in 1997 aged 32. He has developed an international reputation in prostate brachytherapy having successfully treated more than 6,000 patients. Collaborating with the University of Surrey he has built, and leads, an award-winning research team working in the field of prostate cancer. He has established a number of medical courses and has taught the technique of prostate brachytherapy to over 200 consultants across the World.

In 2004 he was appointed Visiting Professor of Urology at the University of Surrey. In the same year he was first to publish the transperineal prostate biopsy technique which has now become the gold standard for prostate biopsy. In 2012 he published the technique of 4D Brachytherapy based on his experience of over 1000 procedures. This one-stage real-time brachytherapy implant using both loose and stranded seeds optimizing the radiation dose to the prostate yet minimizes the side effects has been adopted by centres world-wide.

Professor Langley has published numerous clinical papers and presented the results of his research at many International Conferences. Due to his expertise he was invited to join the Department of Health’s Prostate Cancer Advisory Group. He is also Chairman of the Prostate Brachytherapy Advisory Group and Co-Chair of the Surrey & Sussex NHS Cancer Alliance in Urology.

Dr Sara Khaksar was appointed Consultant Clinical Oncologist at the Royal Surrey County Hospital in 2006. In 2021, she transitioned to primarily private practice, while continuing to play a key role in the Prostate Brachytherapy team at The Royal Surrey.

She has established a specialist practice in prostate cancer and is experienced in all aspects of localised and advanced (metastatic) prostate cancer. Her expertise spans prostate brachytherapy, intensity-modulated radiotherapy (IMRT), adaptive MR-guided stereotactic radiotherapy, salvage radiotherapy after prostatectomy and systemic therapies for metastatic prostate cancer, including hormone therapy, chemotherapy, immunotherapy and Radium 223 and Lutetium PSMA treatment.

Dr Khaksar studied medicine at the University of Wales, Cardiff. Her clinical oncology training took place in London at Charing Cross Hospital, The Hammersmith Hospital, Mount Vernon Hospital and The Royal Marsden Hospital. She gained advanced specialist training during a clinical fellowship at the Princess Margaret Hospital in Toronto. In 2004 she joined the brachytherapy team at the Royal Surrey as a Prostate Brachytherapy Fellow. Here she audited, presented and published the results of the centre. Her projects included developing the two-stage procedure into a one-stage real time implant which is now established practice.

During her tenure as a Consultant at the Royal Surrey, Dr Khaksar made contributions to research as the principal investigator for numerous clinical trials. She served as Prostate Brachytherapy Clinical Lead and Radiotherapy Development Lead for the Cancer Centre. Her interests also include medical education and she held the position of College Tutor for Clinical Oncology Trainees from 2018 to 2021.

Dr Carla Perna is a highly regarded consultant clinical oncologist based in London, Guildford, and Surrey who specialises in urological cancers, particularly prostate cancer and testicular cancer. With 15 years’experience, Dr Perna is highly proficient in various treatment modalities, including chemotherapy, MRIdian, hormone therapy, immunotherapy, 177 Lutetium PSMA therapy, and radiotherapy such as stereotactic radiotherapy and brachytherapy.

Dr Perna consults privately at Nuffield Health Guildford Hospital, GenesisCare Guildford, GenesisCare London Cromwell Hospital, and London Bridge Hospital. As well as this, she has also served as a specialist advisor for uro oncology and an MRI specialist for GenesisCare since 2019. Dr Perna provides 400 prostate brachytherapy treatments each year, utilising both the low-dose-rate and high-dose-rate techniques.

Dr Perna holds an MBBS from Università degli studi di Palermo. Following this, she completed higher specialist training in radiation oncology, before going on to accomplish a prestigious clinical fellowship at University College London Hospital, where she dedicated two years to formal research in pelvic radiotherapy. Additionally, Dr Perna holds the FRCS equivalent from the Royal College of Radiologists.

Beyond her practice, Dr Perna continues to make notable contributions to the field of clinical oncology. As a principal investigator, she has led several urological trials exploring radiotherapy techniques with hypo fractionation and SpaceOAR, as well as systemic treatments including Theranostic applications such as Lutetium PSMA for metastatic prostate cancer.

https://www.topdoctors.co.uk/doctor/carla-perna
https://carlaperna.co.uk/
https://www.doctify.com/uk/specialist/dr-carla-perna
https://www.genesiscare.com/uk/our-doctors/dr-carla-perna

Professional qualifications
MBBS- Aristotle University of Thessaloniki Medical School (1992-1998)
MRCP -Royal College of Physicians, Edinburgh, November 2007
FRCR-Royal College of Radiologists, March 2013

Post-graduate degrees
MSc in Oncology, University of Newcastle Medical School, July 2008
MD (Res) student-ICR-University of London-2016

Mr Mikropoulos is a Clinical Oncologist with significant experience in treating a range of solid tumours. He is actively involved in cancer research and aim to lead innovative projects that will have a significant impact on patient care. His research interests are mainly focused on Genomics, Precision Medicine, Prostate Brachytherapy and Stereotactic Radiotherapy

Current appointment June 2019 to now:
Mr Mikropoulos is a Consultant Clinical Oncologist at St Luke’s Cancer Centre where he care for patients with prostate, bladder, testicular cancer, penile cancer and Colorectal cancer, he also provides Lymphoma Radiotherapy and SABR for oligometastatic cancers and prostate brachytherapy.

Research Experience
PI for SABRE prostate SABR RT trial; ARASTEP; WAYFIND-R